Fig. 6 | Nature Communications

Fig. 6

From: Lack of beta-arrestin signaling in the absence of active G proteins

Fig. 6

DMR profiles of ligand-activated β2AR, AT1R, and V2R in WT and Δβarr1/2 HEK cells. ac DMR recordings of β2AR in wild-type (a), Δβarr1/2 (b), and ΔGs (c) cells treated with Isoproterenol (Iso) or Carvedilol (Carv). df DMR recordings of AT1R wild-type (d), Δβarr1/2 (e) and ΔGsix cells+PTX (f) treated with AngII or SII. gi DMR phenotyping of V2R in wild-type (g), Δβarr1/2 (h), and ΔGsix cells+PTX (i). DMR traces shown are representative (mean + s.e.m.) for one out of three independent experiments, each performed in triplicate

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