Fig. 6

Protection from H60⁺EL4 tumor cells by J15 CD8⁺ escapee T cells in Con-H60 recipients. a Schematic presentation of the experimental procedure. H60⁺EL4 or H60⁻EL4 tumor cells (5 × 10⁵) were injected s.c. into the recipients of CD45.1⁺J15 BMT at 6 weeks after BMT. b The tumor volume and survival rate of CD45.1⁺J15 BMT recipients were periodically measured and plotted. The mean survival times (MST) of tumor-implanted recipients are indicated in parentheses. Data represent two independent experiments (n = 6 mice/group/experiment). P-values were determined by the log-rank (Mantel–Cox) test. c In vivo BLI of tumor-injected recipients. Recipients of CD45.1⁺J15 BMT after s.c. injection of 5 × 10⁵ H60⁺EL4-Luc or H60⁻EL4-Luc cells were imaged for luminescence signal emission from the tumor cells on days 0, 3, 7, 14, 21, and 28 post-tumor implantation. The emitted luminescence signal values are plotted. Representative data from two independent experiments (n = 3/group/experiment) are shown