Fig. 2
From: GWAS of epigenetic aging rates in blood reveals a critical role for TERT
Genome-wide meta-analysis for intrinsic and extrinsic age acceleration in blood. Manhattan plots for the meta-analysis P-values resulting from 15 studies comprised of 9907 individuals. The y-axis reports log transformed P-values for a intrinsic epigenetic age acceleration (IEAA) or b extrinsic epigenetic age acceleration (EEAA). The horizontal dashed line corresponds to the threshold of genome-wide significance (P = 5.0 × 10−8). Genome-wide significant common SNPs (MAF ≥ 5%) and low frequency SNPs (2% ≤ MAF < 5%) are colored red and cyan, respectively
