Table 3 Comparison of GT-B active sites

From: Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli

Enzyme

PDB

Inverting/ retaining

  

Catalytic base

  

Pyrophosphate

 

Pyro phos.

Ribose

LpxB

5W8X

I

E15

S17

D98

P198

G199

S200

R201

T277

E281

MurG

1NLM

I

NA

T16

H19

G190

G191

S192

NA

T266

E269

Δ24PmST1

2IHZ

I

NA

S36

D141

NA

NA

NA

NA

NA

E338

MshA

3C4V

R

NA

NA

NA

NA

NA

NA

NA

NA

E324

NST

2YK7

I

NA

NA

D258

NA

NA

S322

NA

NA

E300

PimA

2GEJ

R

Y9

NA

NA

NA

NA

NA

R196

NA

E282

WaaA

2XCU

I

NA

NA

E31

NA

NA

NA

R212

NA

E276

  1. Residues shown are those found to be analogous to LpxB active site residues by comparison of listed crystal structures
  2. NA, not applicable, indicates that an analogous residue could not be unambiguously assigned