Fig. 2
From: Detecting RNA base methylations in single cells by in situ hybridization
MR-FISH can detect single methylated m1G and m3U bases. Discrimination by Molecular Beacons between methylated and unmethylated synthetic RNA target sequences of a RrmA and b RsmE. Scatter plots of red and green fluorescence intensities of bacteria stained by MR-FISH using hybridization probes for RrmA (c; n = 1567 (parent strain) and 966 (ΔrrmA) cells) and RsmE (d; n = 2266 (parent strain) and 1894 (ΔrsmE) cells) modifications. Log-normally distributed ratios of red fluorescence intensity (IR) to green fluorescence intensity (IG) of bacteria stained by MR-FISH using hybridization probes for e RrmA and f RsmE
