Fig. 2
From: The effects of death and post-mortem cold ischemia on human tissue transcriptomes
Effect of PMI on gene expression. a Distribution of the number of genes with significant temporal changes per tissue between at least two time intervals. Brain and pituitary have longer PMIs, only within last two time intervals, thus less interval ranges to detect significant changes. b Heatmap with the number of genes with significant changes detected between two consecutive time intervals. c Heatmap with normalized expression values for genes with changes in liver. The top bar is the color code for the PMI interval of each sample, the right bar list genes involved in the various functions and pathways. On the side we highlight sub-clusters with different patterns of temporal expression. d Example of four genes with different temporal patterns. RNASE2 is a non-secretory ribonuclease involved in several functions; HBA1 is alpha hemoglobin involved in oxygen transport; EGR3 is a transcriptional regulator involved in early growth response; CXCL2 is a chemokine gene that encodes secreted proteins involved in immune and inflammatory processes
