Fig. 2

Transcriptional decomposition across chromosomes. a PI and PD components (mean ± standard deviations), as well as H3K27me3 and H3K36me3 ChIP-seq data for GM12878, HeLa-S3 and HepG2 cells at locus chr1:145,000,000–180,000,000. b, c Loci (highlighted in a) around KCNN3 (b) and NOS1AP (c) genes showing cell-type-specific PD signals. The PD and PI signals and ChIP-seq data associated with repression (H3K27me3) and activation (H3K36me3) are shown