Fig. 4
From: Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential
Leukemogenic potential of expanded clones. a Percentage of t-AML/t-MDS cases (n = 134) harboring a mutation in the indicated gene. b Percentage of patients who after cytotoxic therapy (n=81) had an expanded clone harboring a variant in the indicated DNA damage response gene compared to the percentage of t-AML/t-MDS patients (n = 134) with a mutation in the same gene. c Same as b except that the comparison is between lymphoma patients at the time of autologous transplant (n = 69) and t-AML/t-MDS patients with a primary diagnosis of lymphoma (n = 48). For b, c significance was determined with an exact logistic regression through use of a joint test. *P < 0.05; **P < 0.01; ***P < 0.001
