Fig. 5
From: 3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection
HBV-infected 3D PHH cultures predict human host responses. a Cytokine XL antibody array of uninfected 3D PHH cultures and cultures infected with 100 GE/cell patient-derived HBV for 10 days. b–g Comparison of the longitudinal protein expression values of b IL-8, c MIP-3α, d CXCL10, e VEGF, f Serpin E1, and g MCP-1 between HBV-infected patients, healthy controls, and 3D PHH cultures infected with patient-derived HBV (100 GE/cell) as well as correlation of each cytokine with HBsAg (HBV-infected patients and infected 3D PHH cultures) and HBeAg (infected 3D PHH cultures) levels. Data shown are mean ± SD of three independent experiments. p-values calculated by two-way ANOVA with Bonferroni post-test
