Fig. 1 | Nature Communications

Fig. 1

From: Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation

Fig. 1

Gut microbiota maturation of high risk for asthma (HR) subjects is significantly distinct from that of healthy controls (HC), and influenced by oral Lactobacillus rhamnosus (LGG) supplementation. a Compared to HC (n = 29) subjects, HR placebo supplemented (HRP; n = 15) participants exhibit a significant delay in bacterial alpha diversification over the first year of life (β ANCOVA, p = 0.02), which is partly rescued by LGG supplementation (HRLGG; n = 10; β ANCOVA, p = 0.63). Error bars indicate standard-deviation from the mean. b HRP (n = 15) and c HRLGG (n = 10) infants exhibit significant differences in bacterial beta diversity across all of the time points assessed (Unweighted UniFrac distance; R2 and p-values calculated using PEMANOVA). d HRLGG (n = 10) infant gut microbiota is significantly (though marginally) more similar to HC (n = 29) subjects during the period of LGG supplementation (Unweighted UniFrac distance; Bonferroni corrected t-test). Whiskers extend to 95% confidence interval

Back to article page