Fig. 4

Multifunctional microfluidics enabled by ADAPTS. a Antifouling capability of a microchannel with dynamic pockets before and after continuously transporting first RB and then octane. No fouling or soaking of the channel was observed. Conventional PDMS microchannels were injected with RB and octane at the same conditions. A significant amount of residual RB is left on the walls of PDMS microchannels. Octane swells PDMS and damages the entire microchannel. Scale bar is 100 μm. b Antifouling capability of a microchannel with dynamic pockets before and after continuously injecting blood. No fouling or soaking of the channel was observed. A liquid-free PTFE microchannel was injected with blood at the same conditions. A significant amount of residual blood is left on the walls of PTFE microchannel. Scale bar is 2 mm. c Liquid gating function of the microchannel inside the ADAPTS. The results are shown for the channel size of the length 6 cm, height 200 µm, width 5 mm; average pore size of ~5 µm and flow rate of 500 µL/min (I) and 2.5 mL/min (II). d Fluorescent particles inside the microchannel with dynamic pockets show fluorescent signal, while the signals are blocked by the channel with air pockets only. Scale bar is 100 μm. Optical images of blood transport inside the microchannels with or without dynamic pockets indicates that the blood flow is visible inside the ADAPTS. Scale bar is 2.5 mm