Fig. 5
From: Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications
Stability of Gd complexes. a–c RP-HPLC traces of [GdL2A]−, [GdL2B]− and [GdDOTA]− in 1N HCl at room temperature over time. d Change in peak area integration over time. Quantitative analysis with RP-HPLC suggest [GdL2A]− and [GdL2B]− exhibit much higher stability than [GdDOTA]− in acidic medium at room temperature. Error bars for [GdL2A]- and [GdL2B]- refer to the standard error of mean (S.E.M.), statistical data fitting analysis (n = 3; s.e.m.)
