Fig. 1 | Nature Communications

Fig. 1

From: A systematic approach to the development of a safe live attenuated Zika vaccine

Fig. 1

Infectious clone-rescued small-plaque ZIKV and unique M protein mutation. a Plaque phenotype on Vero cells and mutations of infectious clone-derived ZIKV, based on sequences of small-plaque variants (white arrow) purified from C6/36-derived PF13 stock. b The amino acid sequences of various ZIKV strains of different lineages (Asian and African) and both wild-type and vaccine strains, if available, of various mosquito-borne flaviviruses were aligned and the unique M66V mutation in DN-2 is highlighted in red and indicated with an arrow

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