Fig. 1
From: Expansion of functional personalized cells with specific transgene combinations
Overall strategy and proliferation capacity of transduced cells. a Outline of the experimental strategy followed to establish cell lines. b Growth curves of various human and murine cell populations upon lentiviral transduction with the library of 33 genes (black lines), as well as of mock-infected primary cells (control, red lines). Cumulative population doubling levels (PDL) of the established cell lines as well as of respective primary cells are given for the indicated time period after infection (day 0). Transducing HUVECs with a single gene (MYC) resulted in limited expansion of the cells (marked by an arrow)
