Fig. 8
Psychosis is associated with reduced network connectivity in states A4 and C4. a The colored aspects of the cortex reflect regions estimated to be within the A, B, and C aspects of the frontoparietal control network39. b Functional connectivity matrices for the 50 left and right hemisphere regions of the frontoparietal control network shown for the healthy comparison and patient groups in states A4 and C4. Functional connectivity difference matrices were obtained by an analysis of variance of z-transformed Pearson correlation values after linear regression of the effects of age, sex, handedness, and scanner bay. Group differences significant at false-discovery rate q ≤ 0.05 are shown in each panel to the lower right of the unthresholded matrix. c The colored aspects of the cortex reflect regions estimated to be within the A, B, C, and D aspects of the default network. d Corresponding connectivity matrices are shown in 52 left and right hemisphere regions of the default regions for states A4 and C4. Reduced default network connectivity in psychosis is preferential to state A4
