Fig. 1 | Nature Communications

Fig. 1

From: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

Fig. 1

Open chromatin sites (DHSs) within adipocyte promoter CHi-C chromosomal interactions show significant enrichment in cis expression. Enrichments in cis expression with error bars for different categories using LD score regression analysis (see Methods). For the horizontal axis labels, the value in parentheses shows the percentage of SNPs contained within the respective annotation category that contributed to the enrichment calculation. For the significance threshold after Bonferroni correction above each bar, * indicates a p-value < 0.05; **, a p-value < 0.001; and ***, a p-value < 0.0001, respectively. The p-values were estimated based on Z scores calculated from the normal distribution. Error bars represent jackknife standard errors around the estimates of enrichment

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