Fig. 10
From: Divergent midbrain circuits orchestrate escape and freezing responses to looming stimuli in mice

Summarized diagram illustrating the circuit mechanism underlying the action selection between dimorphic defensive behaviors. a Looming visual stimuli mimicking predator of mice trigger either Type I (escape-freezing) or Type II (freezing-only) defensive behavioral pattern. b Looming visual stimuli were encoded by PV+ neurons in retinal-recipient layers (SuG and Op) of the SC. Distinct groups of SC PV+ neurons transmit looming visual signals to the PBGN and LPTN. PBGN and LPTN then send these signals to the downstream targets to determine the behavioral outcome of mice, either Type I or Type II defensive behavioral pattern