Fig. 4

Gene expression of responding NK cells at single-, 100-cell, and whole-transcriptome levels. Gene expression heat map displaying top 10 upregulated and top 10 downregulated of 96 pre-selected genes involved in NK responses across stimulation conditions, ranked by fold change. Each column represents expression at the single-, 100-, and bulk-cell levels. Data represented are from three donors and three stimulation conditions, K562, ADCC, and IL-12/IL-18. Expression threshold (ET) values were calculated based on CT values (40-CT) obtained from the qPCR data and fold change was determined by comparison of ET values