Fig. 8 | Nature Communications

Fig. 8

From: Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccination

Fig. 8

Cell surface expression of NKG2C and gene expression of CD57+NKG2C+ NK cells in vaccinated individuals. a Flow cytometric gating strategy of sorted CD57+NKG2C+ NK cells. b Graphical analysis of frequency of CD57+NKG2C+ NK cells in vaccinated individual’s pre (blue)- and post (red) vaccination. Wilcoxon matched-pair sign-rank test was used to determine significance between frequencies of each group. c Volcano plot displaying upregulated (red) and stably expressed (gray) pre-selected genes, involved in NK cell-mediated responses to MVA vaccination. Size of each data point is calculated as −log10(p-value) × log2(FC), p-value cutoff p < 0.05, fold change cutoff > 2 or <1/2. Transcriptional analysis from 11 vaccinated individuals and 1 independent experiment is represented

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