Fig. 3
Enriched ssDNA library validation. a Staining of the tissue from the NB case that was used during the selection process with unenriched library (round 0), compared to the enriched EL-NB library (round 6; upper panel: ×4, 100 µm scale bar, lower panel: ×60, 14 µm scale bar); b Staining of tissue from an NB case not used during the selection process with unenriched library (round 0), compared to the enriched library EL-NB (round 6; upper panel: ×4, 100 µm scale bar, lower panel: ×60, 14 µm scale bar); c Staining of the tissue from the benefiter case employed for counter selection in the enrichment of EL-NB, using the output ssDNAs from round 3 (left, ×20, 40 µm scale bar), compared to the output ssDNAs from round 5 (right, ×20, 40 µm scale bar). No adjustment was applied to images from microscopy
