Fig. 3 | Nature Communications

Fig. 3

From: The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis

Fig. 3

Structure of the ngε_1/ngζ_1 TA complex and substrate binding mode. a Surface representation of ngζ_1 colored according to the electrostatic surface-potential and ngε_1 depicted as ribbon model (forest-green). b Ribbon representation of ngζ_1 at the same orientation as in a. Structural elements involved in topological rewiring are highlighted in red (strand)/pink (helix) and dark-yellow (strand)/yellow (helix). The C-terminal OB-fold domain is colored in red. Coloring is performed similar as in Supplementary Fig. 1. c, d Close-up view of the active site of ngζ_1 with the bound UNAM (c) and UNAM-4P (d) molecules shown as stick model. Fo-Fc electron density map contoured at 3σ with the ligand omitted before refinement is shown as a mesh

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