Fig. 4
Structure comparison of HA RBS from different strains. a The HA RBS conformations of HK68 E190D (gray), Wy03 (orange), Fin04 (green), HK05 (pink), Bris07 (blue), and Vic11 (yellow) were compared by aligning their receptor-binding subdomain (HA1 residues 117–265)24. Pairwise comparisons of the 190-helix region are also shown. Cα of residue 190 for each HA is shown in a sphere representation. b The distances between the Cα of residues 186 (Cα186) and the Cα of residues 228 (Cα228) and between the Cα of residues 190 (Cα190) and the phenolic oxygen of residue 98 (OH98) in different strains were measured. HK68: PDB 4FNK (ref. 59) and PDB 4WE4 (ref. 66). Fin04: PDB 2YP2 (ref. 9). HK05: PDB 2YP7 (ref. 9). Vic11: PDB 4O5N (ref. 23)
