Fig. 1 | Nature Communications

Fig. 1

From: How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin

Fig. 1

Quantifying the fraction of virions with each mutation that escape antibody neutralization. This figure shows hypothetical data for four viral variants. a Virions with the V1K mutation (orange) completely survive an antibody concentration where most other virions are neutralized. b This resistance is manifested by a large shift in V1K’s neutralization curve. c For each dotted vertical line drawn through the neutralization curves in b, we calculate the fraction of virions with that mutation that survive the antibody, and indicate this fraction by the height of the letter corresponding to that amino acid at that site. d–f Similar data to the first three panels, but now V1K has only a small antigenic effect, and modestly increases the fraction of virions that survive antibody treatment

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