Table 2 Cox proportional hazard regression analyses for overall survival

From: TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling

Clinical features

Univariate analysis

Multivariate analysis

HRa (95% CIb)

P value

HR (95% CI)

P value

Gender

0.881 (0.654–1.187)

0.406

  

Age

1.294 (0.964–1.736)

0.086

  

Grade

0.994 (0.667–1.483)

0.978

  

Location

0.572 (0.434–0.755)

<0.001

0.484 (0.353–0.664)

<0.001

Differentiation

1.411 (1.142–1.742)

0.001

1.461 (1.169–1.827)

0.001

Tumor invasion

1.618 (1.245–2.103)

<0.001

1.283 (0.920–1.790)

0.142

LN metastasis

2.080 (1.548–2.795)

<0.001

1.520 (0.922–2.505)

0.101

Distant metastasis

2.738 (1.437–5.217)

0.002

0.618 (0.251–1.525)

0.297

Clinical stage

2.319 (1.718–3.130)

<0.001

1.534 (0.934–2.518)

0.091

T15 expression

1.868 (1.383–2.524)

<0.001

1.538 (1.127–2.098)

0.007

  1. a Hazard ratio
  2. b Confidence interval
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