Fig. 1 | Nature Communications

Fig. 1

From: Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

Fig. 1

Cas9 expression in the brain of TVA/Cas9 mouse strains. a, b Immunofluorescence staining performed on brain sections of four-week-old Ntv-a; Nes-Cre; LSL-Cas9 and Gtv-a; hGFAP-Cre; LSL-Cas9 mice with antibody against EGFP (Cas9), NESTIN and GFAP. CAS9 is widely expressed in the whole brain and co-localize with NESTIN and GFAP in the subventricular zone. Left panels: whole brain section; right panels: higher magnification of the left panel inset. Scale bars: left panels, 500 μm; right panels, 100 μm. LV lateral ventricle

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