Table 2 Summary of nucleotide variants described with targeted amplicon sequencing
From: Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections
Amplicon region (amplicon length) | Sampled infections | Sequenced amplicons | Total variant sites | Nonsyn. variant sites | Singleton variants | Common variantsa | Highly variant sitesb |
|---|---|---|---|---|---|---|---|
CSP (288 nt) | |||||||
Total | 1687 | 3821 | 55 | 50 | 15 | 23 | 12 |
West Africa | 935 | 2147 | 46 | 43 | 8 | 24 | 8 |
East Africa | 752 | 1674 | 41 | 39 | 8 | 23 | 8 |
TRAP (318 nt) | |||||||
Total | 4209 | 8774 | 52 | 52 | 13 | 15 | 5 |
West Africa | 2334 | 4925 | 38 | 38 | 7 | 16 | 5 |
East Africa | 1875 | 3849 | 38 | 38 | 10 | 15 | 3 |
SERA2 (258 nt) | |||||||
Total | 4209 | 9007 | 67 | 67 | 19 | 12 | 16 |
West Africa | 2334 | 5048 | 53 | 53 | 17 | 13 | 12 |
East Africa | 1875 | 3959 | 49 | 49 | 11 | 8 | 11 |
