Fig. 8
From: Gene expression links functional networks across cortex and striatum
Limbic network-biased genes are consistent in independent human and non-human primate datasets. a Schematic illustrating the limbic cortico-striatal network displayed on a bi-hemispheric cross-section of the striatum and the lateral surface of the left hemisphere. b Among the AHBA data, 505 genes displayed overlapping positive differential expression for both limbic striatum and limbic cortex (hypergeometric p ≤ 0.001). c Among the GTEx and Brainspan replication data, 463 genes displayed overlapping positive differential expression for limbic striatum and limbic cortex, 184 of which overlapped with the AHBA limbic network gene set (ps ≤ 0.001). d In macaques, 305 genes displayed overlapping positive differential expression for limbic striatum and limbic cortex, 93 of which overlapped with the AHBA limbic network gene set (ps ≤ 0.001). *p ≤ 0.001
