Table 1 The characteristics of ATAC-Seq samples

From: ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Variable

Tissue

Normal

Early AMD

Late AMD

P value*

No. of samples

Retina

11 (58%)

5 (56%)

9 (53%)

0.99

 

RPE

8 (42%)

4 (44%)

8 (47%)

0.99

Region (macula)

Retina

5 (45%)

2 (40%)

5 (56%)

0.99

 

RPE

3 (38%)

2 (50%)

6 (75%)

0.38

Gender (male)

Retina

5 (45%)

2 (40%)

2 (22%)

0.57

 

RPE

5 (63%)

1 (25%)

2 (25%)

0.41

Age (years)

Retina

84: 79 ~ 92

87: 82 ~ 87

90: 90 ~94

0.09

 

RPE

88: 84 ~ 92

92: 85 ~ 97

90: 89 ~ 94

0.32

Interval (hours)a

Retina

10.1

5.3

6.6

0.01

 

RPE

9.5

4.9

6.8

0.08

  1. *Fisher’s exact test and one-way ANOVA were performed, respectively
  2. aInterval indicates the time from death to procurement of eye