Fig. 2

Diurnal oscillations of hepatic transcription factors. a Rose diagram shows the number of TP-specific TFs of each TP. b Area graph shows the normalized abundance of TP-specific TFs DNA-binding activity and the bioprocess enriched by TP-specific TFs. c Cluster heat maps of the diurnal rhythmic DNA-binding activity of DBPs, TFs, and TCs. The color bar indicates normalized z-scored iBAQ. The upper white to black bar indicates the 2 days’ cycle. Daytime is shown in white, while nighttime is shown in black. d Temporal levels of the abundance of DNA-binding activity of Bmal1, Clock, Cry2, and Bhlhe40 in two consecutive cycles. X axis represents the sampled time points, Y axis represents the relative abundance of DNA-binding activity (normalized z-scored iBAQ) of each protein. e The GO bioprocesses enriched by diurnal rhythmic TP-specific TFs (red) and by all TP-specific TFs (black) of four TPs