Fig. 4
From: Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s
a–c KLP10A-tubulin binding interface. Side views of the complexes indicating KLP10A secondary structure elements making contact with tubulin in the three areas of interaction (I–III). a NMMTapo. b NMMTAMP-PNP. c CTMMTAMP-PNP. KLP10A in blue, SW1 in green, SW2-H4 in magenta, AMP-PNP in red, β-tubulin in orange, α-tubulin in yellow. d Solvent accessible surface of the CTMMTAMP-PNP complex highlighting residues at the tubulin KLP10A interface within contact distance (specific residues making contacts are listed in Supplementary Fig. 5). Residues are color coded according to type. Negative red, positive blue, polar magenta, and non-polar yellow
