Table 2 Single-cell TCR sequencing of Vγ9− Vδ2+ T cells

From: The human Vδ2+ T-cell compartment comprises distinct innate-like Vγ9+ and adaptive Vγ9- subsets

Donor

CDR3δ2

Dδ

Jδ

CDR3δ length

Vγ

Jγ

CDR3γ length

3

CACGSWWGTYTDKLIF

1,3

1

14

8

P1

11

231

CACDTIVGDTLTDKLIF

3

1

15

8

P1

9

CACVRGGGYPRGADKLIF

3

1

16

8

1/2

14

CACDTEGEVNTDKLIF

3

1

14

4

P1

11

261

CACDTRFRPGRSARVVRLTAQLFF

1

2

22

3

P1

14

Liver 1

CACSREQAHTDKLIF

3

1

13

3

1/2

10

CACDTGWGIRGRYTDKLIF

3

1

17

4

1/2

11

Liver 2

CACDRSGARWDKLIF

—

1

13

5

1/2

10

42

CACDARHYWGISTDKLIF

3

1

16

2

1/2

12

CACDARLGEHTDKLIF

3

1

14

ND

ND

ND

CACDRMGDLPSSWDTRQMFF

3

3

18

3

1/2

13

CACGSSWGVSHYTDKLIF

3

1

16

5

1/2

10

CACDLLGDFRTDKLIF

3

1

14

8

1/2

8

CACSVRGHWGRSTDKLIF

3

1

16

8

1/2

14

CACDTRGIGDTLPDKLIF

3

1

16

8

P1

12

CACAHGYWGTPWDTDKLIF

3

1

17

3

P1

11

 

CACDTGDTDTDKLIF

3

1

13

8

P1

13

CACDRLLLGDTDKLIF

3

1

14

ND

ND

ND

CACDTRRTGGRDKLIF

3

1

14

5

1/2

9

CACDKRIRWGNPYTDKLIF

3

1

17

8

P2

10

CACEVPSYEPYWGTKKYTDKLIF

2,3

1

21

3

1/2

11

CACDTGDWGINTDKLIF

3

1

15

8

P1

14

CACDQKYWGGSSTDKLIF

3

1

16

2

P

13

  1. TCRδ sequences of clonally expanded Vγ9− Vδ2+ TCRs from donors expressing a CD27lo/neg phenotype (top section). All TCRδ2 sequences from a representative healthy donor with a CD27hi phenotype (bottom section). Sequences were analysed using IMGT Junction Analysis, which identified V, D and J gene segments used. The table depicts CDR3δ sequences, Dδ usage, Jδ usage, CDR3 length, Vγ usage, Jγ usage and CDR3γ length. Amino acids (aa) at position 5 of the CDR3 sequence (see Methods) are highlighted in bold. ND not determined
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