Fig. 3
Conformational exchange of β2m probed by relaxation dispersion experiments. Selected examples of 15N R1ρ relaxation dispersion curves for wt (red) and D76N (blue) β2m. a The purple, orange, and blue rectangles show respectively residues located at the end of the A-strand, in the CD-loop and EF-loop. Best Lorentzian fits are depicted with solid lines. The difference between 15N R1ρ rates at 3 kHz and the fitted values at 20 kHz spin-lock field are depicted versus the sequence in b. Error bars (s.d.) were obtained from 1000 Monte Carlo simulations
