Fig. 1
From: Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K
PRP4K regulates organ size through the Hpo pathway. a–d Side (top) or dorsal view (middle) of Drosophila adult eyes or late third instar eye imaginal discs expressing diap-GFP3.5 (bottom) of the following genotypes: GRM-Gal4 (a), GMR-Gal4 UAS-Yki (b), GMR-Gal4 UAS-Yki UAS-PRP4K-RNAi (c), and GMR-Gal4 UAS-Yki UAS-PRP4K (d). e Quantification of eye size for the indicated genotypes. f Quantification of GFP signal in the indicated eye discs in anterior and posterior regions relative to the morphogenetic furrow. g–j Drosophila adult eyes containing control clones without (g; white color) or with (i) GMR>Yki, or PRP4K mutant clones without (h; orange color) or with (j) GMR>Yki. (k) Quantification of eye size for the indicated genotypes. l–m Drosophila adult eyes expressing UAS-Sd-GA either alone (l) or in conjunction with UAS-PRP4K-RNAi (m) under the control of GMR-Gal4. n–o Drosophila adult eyes expressing UAS-Wts-RNAi either alone (n) or in conjunction with UAS-PRP4K (o) under the control of GMR-Gal4. p–q Quantification of eye size for the indicated genotypes. Data are means ± s.d. from three independent experiments. N ≥ 5 for each genotype
