Fig. 4
From: Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB
The transmembrane pore is composed of YaxA and YaxB foot domains. a Details of a transmembrane segment of the pore. The YaxAB pore model (YaxA: blue, YaxB: pink) was submitted to the PPM server to delineate the buried hydrophobic membrane surface. Shown are foot domains from one cis-dimer, as well as the neighboring protomers (transparent ribbons). Membrane exposed residues are colored in gold. The golden spheres demarcate the calculated boundaries of the apolar surface. b Hydrophobic surface rendering of the YaxAB model. Gold coloring indicates high hydrophobicity. The golden rectangle delineates the approximate membrane boundaries. c Charge distribution of the pore lumen. The surface is rendered by the qualitative electrostatic representation implemented in PyMOL (Schrödinger, LLC)
