Fig. 3 | Nature Communications

Fig. 3

From: CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens

Fig. 3

Predicting the protective spectrum for a new vaccine (Con H3) of the influenza A/H3N2 strain by CE-BLAST. a Antigenic clustering results between HA epitopes of 679 influenza strains. Strains with identical HA epitopes as the new vaccine were marked in green and labeled as Con H3. The pink region shows the potential antigenically similar or cross-reactive strains to Con H3. The locations of the three strains inside the spectrum are marked in green, whereas the other four strains outside the spectrum are marked in blue. b Inhibition concentration for the seven tested strains with the monoclonal neutralization antibody derived from Con H3-immuned mice. IC 50 values were calculated by fitting

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