Fig. 4
From: CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens
Subtype grouping of dengue virus by CE-BLAST. a 3D antigenic mapping of 28 dengue virus strains based on the serological data from Katzelnick et al.6 by MDS. b 2D antigenic mapping of Fig. 4a. c Antigenic clustering of 47 strains by CE-BLAST similarity score. d Traditional grouping by sequence phylogenetic tree of 47 E protein sequences. e Traditional grouping by structural clustering tree of 47 E proteins based on RMSD scores of the Multiprot19. Strains DENV1/Vietnam/2008-BID-V1937, DENV1/Thailand/1964/16007, and DENV1/Myanmar/2005/61117 were marked with star, dot, and cross, respectively in c–e
