Fig. 2
From: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer
Effect of ESRRG on GC cell growth. a CCK8 assay and b colony formation assay after ESRRG overexpression in AGS and NCI-N87 cells (n = 3). c–f In vivo GC tumorigenesis analysis in xenograft nude mouse models (Flag: n = 6; Flag-ESRRG: n = 7). c ESRRG overexpression inhibited tumor growth in the xenograft nude mouse model. Flag-control, NCI-N87 cells, or an NCI-N87 cell line infected with a Flag-ESRRG overexpression vector (ESRRG-OE), were injected into nude mice and the tumor volume was measured at the indicated time points. d Mice were sacrificed and tumor volumes and weights were measured. Western blot (e) and IHC (f) analysis of mouse samples was then performed. Data represent the mean ± s.d. from the three independent replicates. Student’s t-test was used to examine statistical significance (*p < 0.05, **p < 0.01, ***p < 0.005)
