Fig. 3 | Nature Communications

Fig. 3

From: Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex

Fig. 3

RVM blockade did not block ACC stimulation-induced potentiation of the spinal sEPSC in sham operated rats. a–c One sample (a) and the histogram figures showing the frequency (b) and amplitude (c) of the spinal sEPSC with lidocaine blockade of RVM were potentiated by following ACC stimulation. d Summarized results from 7 SDH neurons with lidocaine injection and ACC stimulation. *frequency: p = 0.01; amplitude: p = 0.02. One-way RM ANOVA. e Summarized results from 6 SDH neurons with CNQX injection and ACC stimulation. *frequency: CNQX injection vs. baseline, p = 0.04, ACC stimuli vs. CNQX injection, p = 0.03; amplitude: p = 0.04. One-way RM ANOVA. f–g Schematic diagram and sample figures showing the lidocaine injection sites on the RVM. #p > 0.05. Bar = 1 mm in g

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