Fig. 7
From: Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity
Proposed cellular heterogeneity and lineage hierarchies within the human breast. a Schematic summary of discovered cell states within the basal and luminal compartment of the human breast epithelium with proposed function, key transcription factors (in white), selected markers (in black) and similarities to breast cancer subtypes indicated in boxes. b Proposed model summarizing the lineage hierarchies within the breast epithelium based on one continuous differentiation trajectory from basal stem cells to three distinct differentiated cell types with overlaid marker genes of interest shown (black on gray bars)
