Table 2 Scope of substratesa

From: Total synthesis of cyrneines A–B and glaucopine C

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  1. aConditions: Enol triflate 15 (0.2 mmol), boronic acid 16 (0.4 mmol), K3PO4 (3.0 equiv) in a mixed EtOH/DMF (v/v = 1:1) solvent (2.0 mL) at room temperature under nitrogen. Isolated yield. The use of K3PO4 instead of K2CO3 was more effective for the coupling of boronic acids without free phenol group
  2. bThe yield was determined based on the 1H NMR spectroscopy because of the contamination of a small amount of inseparable homocoupled product of boronic acid
  3. cThe methyl ester group of the product was partially exchanged to ethyl ester
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