Fig. 2
From: Recurrent rearrangements of FOS and FOSB define osteoblastoma
FOSB fusion in PD7525. a Schematic of the PPP1R10-FOSB fusion. The PPP1R10 exon 16 splice donor site is skipped, resulting in exonisation of part of the intron. A three-nucleotide non-template sequence at the break point then allows an in-frame PPP1R10-FOSB fusion transcript to be produced. b Annotated schematic of the wild-type FOSB transcript with the published break points in the vascular tumours (pseudomyogenic haemangioendothelioma (PHE), epithelioid haemangioma (EH))
