Fig. 8
From: HuR regulates telomerase activity through TERC methylation
A model summarizes the findings in this study. Association of HuR with TERC promotes TERT/TERC assembly through enhancing the methylation of TERC (m5C) in C106. The reported DC-related mutations impair HuR binding (U100A) or the methylation of TERC (U100A, G107U, and GC107/108AG)
