Table 3 Comparison of c-index between the survival path system, BCLC staging system, and AJCC staging system in the internal testing cohort and multicenter testing cohort
Time slice | Number (modeling/all) | Survival path system | BCLC staging system | AJCC staging system | |||
|---|---|---|---|---|---|---|---|
Number of nodes | c-Index (95% CI) | Number of classes | c-Index (95% CI) | Number of classes | c-Index (95% CI) | ||
Internal testing cohort | |||||||
No.1 | 627/627 | 2 | 0.634 (0.632–0.636) | 1 | — | 6 | 0.634 (0.632–0.636) |
No.2 | 562/562 | 4 | 0.695 (0.692–0.698) | 5 | 0.724a (0.721–0.727) | 6 | 0.733a (0.730–0.736) |
No.3 | 367/367 | 8 | 0.747 (0.722–0.752) | 4 | 0.729b (0.725–0.733) | 6 | 0.737b (0.732–0.742) |
No.4 | 271/277 | 10 | 0.774 (0.766–0.782) | 4 | 0.751b (0.743–0.759) | 6 | 0.737b (0.729–0.745) |
No.5 | 210/222 | 11 | 0.764 (0.755–0.773) | 4 | 0.760 (0.749–0.771) | 6 | 0.728b (0.712–0.739) |
No.6 | 171/181 | 11 | 0.756 (0.743–0.769) | 5 | 0.785a (0.755–0.775) | 6 | 0.746 (0.732–0.760) |
No.7 | 125/148 | 8 | 0.820 (0.803–0.837) | 4 | 0.817 (0.801–0.833) | 6 | 0.824 (0.808–0.840) |
Multicenter testing cohort | |||||||
No.1 | 414/414 | 2 | 0.631 (0.628–0.634) | 1 | — | 3 | 0.602b (0.599–0.605) |
No.2 | 359/359 | 4 | 0.689 (0.685–0.693) | 4 | 0.698a (0.694–0.702) | 6 | 0.715a (0.711–0.719) |
No.3 | 233/234 | 7 | 0.725 (0.718–0.732) | 4 | 0.715 (0.709–0.721) | 6 | 0.720 (0.714–0.726) |
No.4 | 181/189 | 8 | 0.790 (0.781–0.799) | 4 | 0.752b (0.742–0.762) | 6 | 0.759b (0.749–0.769) |
No.5 | 131/149 | 7 | 0.778 (0.765–0.791) | 4 | 0.757b (0.745–0.769) | 6 | 0.754b (0.743–0.765) |
No.6 | 113/128 | 7 | 0.769 (0.750–0.788) | 4 | 0.714b (0.695–0.733) | 6 | 0.734 (0.716–0.752) |
