Table 1 List of screened compounds and their targets
From: A microfluidics platform for combinatorial drug screening on cancer biopsies
Compound name | Compound type | Putative target (effect) |
|---|---|---|
ACHP | Targeted | IKK (inhibition) |
AZD6244 | Targeted | MEK (inhibition) |
Cyt387 | Targeted | JAK (inhibition) |
GDC0941 | Targeted | PI3K (inhibition) |
Gefitinib | Targeted | EGFR (inhibition) |
MK-2206 | Targeted | AKT (inhibition) |
PHT-427 | Targeted | AKT, PDPK1 (inhibition) |
Gemcitabine | Cytotoxic | DNA replication (inhibition) |
Oxaliplatin | Cytotoxic | DNA replication (inhibition) |
TNFα | Cytokine | TNFR (activation) |
