Fig. 3
From: FABP4 as a key determinant of metastatic potential of ovarian cancer
Effect of miR-409-3p on tumor progression and FABP4. a, b Effect of miR-409-3p mimic transfection on the a invasiveness and b migration of HeyA8 MDR cells. **p < 0.01. n = 3. c Aggregate tumor mass in orthotopic mouse models of ovarian cancer (HeyA8 MDR cell line) treated with control miRNA or miR-409-3p mimic incorporated in DOPC liposomes. **p < 0.01. n = 3. d Effect of miR-409-3p mimic on the number of nodules. Representative images are shown on the right. **p < 0.01. n = 3. e Distribution of tumor nodules in individual mice after treatment with control miRNA or miR-409-3p mimic. f Effect of treatment with miR-409-3p mimic on the expression of FABP4 (protein) in tumor samples (n = 3) Optical density (OD) is presented. **p < 0.01. g Representative images of immunohistochemical analysis of FABP4 expression in mice treated with control miRNA or miR-409-3p mimic. Bars and errors bars represent the means and the corresponding SEMs for n > 3
