Fig. 5
From: 2D transition metal dichalcogenides with glucan multivalency for antibody-free pathogen recognition
Antibody-free optical detection of bacteria with dex-WS2. a Schematic illustration of the antibody-free optical detection of bacteria with dex-WS2. b Glass microarray and c Optical photographs of E. coli, Salmonella typhimurium, and S. aureus (2×106 CFU) treated with dex-WS2 (25 μg mL−1) (scale bar, 500 μm). d Raman images of the dex-WS2-treated bacteria based on the 2LA(M) peak of dex-WS2 at 352 cm−1, showing the selective recognition of E. coli. e The total intensity of the Raman signal of dex-WS2 bound on three different types of bacteria. f E. coli detection as a function of dex-WS2 concentrations for the extraction of its affinity to E. coli. g Langmuir isotherm for the binding of dex-WS2 to E. coli. All error bars represent a standard deviation from the mean values (n = 4)
