Fig. 2
From: Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
Molecular features of the ParE44 complex with hole-bound 14-mer DNA. a Amino acid side chains that interact with the DNA duplex are shown as ellipses with colouring corresponding to the two subunits of the ParE dimer. Shortest distances between the DNA and the amino acid side chains are given in Ångstroms. The 6 bp DNA section that interacts with ParE is coloured, the solvent-exposed region is not. The top and bottom DNA strands are in purple and pink and are marked by single and double asterisks. X denotes a putative DNA intercalating AMP-PNP molecule shown throughout in red. The potential weakly interacting amino acid K313 is greyed. b, c Front and top views of the DNA–protein interaction, with the uninvolved N-proximal GHKL ParE region greyed out. Arrows from/to the zoom-in d, e showing the top (*) and bottom (**) DNA strand interaction sites indicate the direction of views displayed in d, e. Residues targeted for mutagenesis are underscored
