Fig. 8
From: Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
Overlap between the dimerized yeast topoisomerase II ATPase domain (Protein Data Bank 4GFH])31 (shown in yellow) and S. pneumoniae topoisomerase IV ATPase domain (through-hole DNA bound complex; shown in blue). AMP-PNP molecules are shown in red, and DNA is shown in pink/yellow for backbone/bases, respectively. The additional eukaryotic topo II-specific loop is shown in red. The structure indicates a potential clash between the bound DNA and the 22-amino acid long insertion loop in the eukaryotic topoisomerase II structure (Supplementary Fig. 8)
