Fig 8

PPC cells with reversed selectivity exhibit stronger modulation by engagement and by error trials. a Proportion of significantly responsive V1 (top) and PPC (bottom) neurons with stable stimulus selectivity (Stim A, 0°; or Stim B, 90°) or reversed selectivity (Go or No-Go). Cells with non-significant selectivity either before or after reversal are categorized as non-selective (NS). b Boxplots (with center line as median, box as interquartile range, and whiskers as 1.5 × IQR) of engagement modulation index for each response group, computed as the mean before and after reversal. “Go”-selective neurons (green) show stronger engagement modulation, i.e., weaker passive responses, than stimulus-selective neurons (red or blue). c Boxplots of error modulation index for each response group, computed by comparing False Alarm trials with Correct Reject trials both before and after reversal. “Go”-selective PPC neurons show stronger error modulation (green) than stimulus-selective neurons (red or blue). d Responses of two PPC neurons with stable selectivity to Stimulus A both before and after reversal of reward contingency. Colors indicate stimulus (red, A; blue, B) and dark, dashed lines indicate passive trials. These neurons show a robust passive response in both conditions, and have a low engagement modulation index. e Same as d but for two PPC neurons with reversed selectivity after reversal of reward contingency. These neurons show virtually no passive response in both conditions, and have a high engagement modulation index