Fig. 9 | Nature Communications

Fig. 9

From: TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins

Fig. 9

TMEM106B expression is elevated in human lung adenocarcinomas and predicts for poor prognosis. a Overall survival and b disease-free survival plots of lung adenocarcinoma patents with elevated expression of TMEM106B in TCGA (provisional, n = 517) data set. Graphical representation of respective case numbers and median survivals are shown below. c Schematic of model for TMEM106B-mediated deregulation of lysosomal function in cancer cells

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